INSTITUTE OF BIOMETRY AND MEDICAL INFORMATICS

Health Informatics

Health informatics concerns the planning and development of health information systems as well as designing e-learning and grid computing solutions. In the field of magnetic resonance imaging and spectroscopy, experimental MRI involves the introduction, use and optimisation of new mensuration apparatus and methods. The Neuroimaging research group is focused on functional and structural brain imaging approaches based on magnetic resonance imaging. In particular, research is being conducted into ways of visualising nerve fibers and brain-computer interfaces using real-time fMRI.

Molecular MR analysis and imaging

In addition to image processing, signal processing is one of the main areas of research in the field of health informatics and encompasses signal generation, detection and processing as well as the corresponding analyses. All diagnostic methods are based on the detection of a specific variable (charge, nuclear spin, absorption/transmission, density, etc.). MR analytics and imaging is about using these properties to extend existing diagnostic methods, whereby the primary focus is on magnetic resonance (MR) procedures. The Otto von Guericke University Magdeburg’s Institute for Biometrics and Medical Informatics (IBMI) has set itself five research priorities in this field:

1. Active ingredients and contrast media

Detecting molecules in a physiological environment often presents a major challenge: samples can change as a result of such things as oxidation processes and the detection limits of the markers to be examined can be too low, which is why, for example, one component of new contrast agents are heterocores. This requires new pulse programmes and the adaptation of image processing methods. More ...

2. Developing molecular temperature probes

Numerous biochemical processes are influenced by temperature. Inflammations, for example, are associated with an increase in temperature. Yet, local in vivo measurements often turn out to be non-trivial. However, it is also possible to determine "temperature", as a variable indirectly using parameters such as image contrast or the chemical displacement of an MR signal. More ...

3. Magnetic resonance hyperpolarisation

One major disadvantage of magnetic resonance approaches is their lack of sensitivity: so-called hyperpolarisation techniques are used to reduce the measurement period and increase sensitivity. The field of health informatics involves writing new pulse programmes as well as adapting existing ones. More ...

4. Low-field MR spectroscopy

By contrast with high-field MR spectroscopy, low-field MR spectroscopy combines all detected signals of a given isotopic type; chemical displacements play no role, in addition to which the detection limit is increased. Nevertheless, simulating the recorded data could identify substance/sample-specific patterns and appropriate data analysis programmes need to be written. More ...

5. Developing new MR coil systems

The research group has set itself the goal of furthering the development of high-field MRI systems, with a particular focus on simulation-supported MR coil development. MR coils are the metrological interface between man and machine and provide a non-invasive insight into the human body. More ...

Neuroimaging

Real-time fMRI

It is possible to analyse the brain activation of test persons during a functional MRI examination using real-time fMRI, a technology that enables such things as the implementation of brain-computer interfaces, which are used for neurofeedback or the control of external systems. More ...

Brain-computer interfaces for virtual reality navigation

The objective of this project is to design and implement a virtual reality (VR) stimulus environment for real-time FMRI studies. VR refers to a computer-simulated environment that conveys synthetic experiences to the users. The purpose of this more profound visualisation technology is to make everyday processes more realistic and to increase the subject’s attention through increased interactions with the simulated world. More ...

Diffusion Tensor Imaging (DTI)

DTI is used to map the movement of water molecules in tissue. Advanced caluclations can trace nerve fibre routes in highly anisotropic tissues such as white brain matter. More ...

Information systems

Scientific Computing

The objective of scientific computing in the field of medicine is to provide high-performance computing resources for health informatics, biometrics and the neurosciences. The server farm, which consists of eight Apple Xserves running Mac OS X.5 and 16 HP Blades running Suse Linux 11.1, was configured as a computing cluster for high-dimensional MRI data calculations. In addition to the server farm, the institute's own PC pool, which comprises 26 PCs each with 4 CPUs, is also used for calculations. More ...

E-learning

As part of the Otto von Guericke University Magdeburg’s Medical Faculty’s e-learning concept, our institute is involved in the development and implementation of case-based learning concepts and the introduction of a collection of teaching materials. More ...

 

 

Last Modification: 23.02.2021 - Contact Person:

Sie können eine Nachricht versenden an: Webmaster
Sicherheitsabfrage:
Captcha
 
Lösung: