INSTITUTE OF BIOMETRY AND MEDICAL INFORMATICS

Markus Plaumann

Deputy Director

Dr. rer. nat. Markus Plaumann

Institute of Biometry and Medical Informatics
Leipziger Str. 44, 39120 Magdeburg,   vCard
Tasks
  • Management of the lab for the synthesis, cell culture and NMR ("Haus 28")
  • Management of the Data Trust
  • Teaching coordination of Biometry and Medical Informatics

 

 

CV and Publications

Professional career

2006 Diplom in Chemistry (University of Bremen)

2010 Doctorate (University of Bremen) 

 

Publications

 

Projects and Research Focus

Projects

  • Data Trust Association Biomedical Research Data State of Saxony-Anhalt [01.01.2022 to 31.12.2024]
  • Independent parahydrogen-induced two-phase hyperpolarizer for ultra-low field and ultra-high field MR (2P-PHIP) [01.01.2022 to 31.12.2024]
  • Construction of an LED unit for light-induced hyperpolarization of physiological substances [02.01.2018 to 31.12.2023].

Completed projects

  • Development of molecular MR temperature probes
  • Fluorinated boron clusters in cell culture
  • Parahydrogen-induced nuclear spin hyperpolarization of fluorinated substrates - standard PHIP
  • Parahydrogen-induced nuclear spin hyperpolarization - studies using the SABRE method
  • Enhancement of MR sensitivity of 19F biomarkers and PET-analogous 19F-labeled receptor ligands by para-hydrogen-induced polarization

Research focus

19F NMR spectroscopy and MR imaging
  • Enhancement of MR signals by parahydrogen-induced hyperpolarization (PHIP: PASADENA, ALTADENA, SABRE) and photo-CIDNP
  • Cell labeling with MR-sensitive fluorinated substances for non-invasive observation of cell migration in tumor treatment
  • Temperature determination using fluorinated markers and MR spectroscopy
  • Synthesis and characterization of new water-soluble fluorinated compounds
Viability measurements in cell culture
  • Review of the toxicity and stability of organic compounds regarding their toxicity and stability on fibroblasts and melanoma cells
Courses
  • Lecture and seminar Q1 Medical Informatics (further Information: Moodle)
  • Lecture/Exercise: "Medicinal Chemistry" at the University of Bremen
  • Practical course: "Structure elucidation of organic compounds" at the University of Bremen

Last Modification: 24.01.2024 - Contact Person:

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